Our Responsibility to this House of Prayer in which we dwell

In today’s Gospel passage from Luke we read: Jesus entered the temple area and proceeded to drive out those who were selling things, saying to them, “It is written, My house shall be a house of prayer, but you have made it a den of thieves.” 

Isn’t all of God’s creation sacred? How do we profane it? What is our responsibility toward this house of prayer in which we dwell?